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For research published in 2022 study in the journal Food and Chemical Toxicology, scientists examined “the genotoxicity and the intracellular reactive oxygen species induction by physiologically relevant concentrations of three different TiO2 nanomaterials in Caco-2 and HT29-MTX-E12 intestinal cells, while considering the potential influence of the digestion process in the NMs’ physiochemical characteristics.” They found a “DNA-damaging effect dependent on the nanomaterial,” along with the micronucleus assay suggesting “effects on chromosomal integrity, an indicator of cancer risk, in the HT29-MTX-E12 cells, for all the tested TiO2 nanomaterials.” Researchers concluded that the results showcase “evidence of concern” regarding titanium dioxide used as a food additive.

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Ponceau 4R, also known as Red No. 40, is a synthetic azo dye that is commonly used as a food coloring. It has a bright red color and is approved for use in the United States, Canada, and the European Union. In the cosmetics industry, Ponceau 4R is used as a colorant to add vibrant hues to lipsticks, blushes, eyeshadows, and other makeup products. It is known for its stability and compatibility with other ingredients, making it a popular choice among manufacturers.

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Overall, universal type products like R996 are essential components in the production of high-quality paints. Their unique properties, including bright white color, high opacity, UV resistance, and versatility, make them ideal choices for a wide range of applications. Whether used in interior or exterior paints, industrial coatings, or automotive finishes, R996 and other titanium dioxide pigments play a critical role in creating paints that are durable, attractive, and long-lasting.

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